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 Brand name: rosiglitazone
Generic name: avandia, Rosiglitazone
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Significantly more female patients who received rosiglitazone experienced fractures of the upper arm, hand, or foot, than did female patients who received either metformin or glyburide. The majority of the fractures in the women who received rosiglitazone were reported in the upper arm, hand, and foot. Women may also be more likely than men to have bone fractures in the upper arm, hand, or foot while taking metformin and rosiglitazone. Overall, anemia and edema were generally mild to moderate in severity and usually did not require discontinuation of treatment with rosiglitazone. The majority of the fractures in the women who received rosiglitazone occurred in the upper arm, hand, and foot.

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